The new four-story, 139,000-square-foot Virginia Tech Carilion Biomedical Research building expands biomedical research on the Virginia Tech Carilion Health Sciences and Technology Campus. It connects to an existing four-story, 152,000-plus-square-foot Virginia Tech Carilion School of Medicine and Research Institute via an elevated walkway. The original building has a medical school, research institute and lower-level parking.

The expansion portion serves as a hub for five major thematic areas: brain health and disorders, cardiovascular science, infection diseases and immunology, metabolism and obesity, and body device interfaces. It houses next-generation instrumentation, including those for molecular, cellular, whole-body imaging and computing. There are also wet laboratories, requiring direct ventilation and specialized piped utilities for water and various gases, MRI and CT scanning, high-resolution electron microscopy, necropsy and pathology. To introduce some natural elements, this new addition features an atrium and multiple green roofs.